| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f1a611fd02e9b1659794e3b6f87e833 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-6826
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0261
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0295
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0275 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-0295
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-026 |
| filingDate |
2020-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6e228a953343868d12a003e2e280f14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce787de524fa8dca6711e0ccdedc2b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9f16c320dd846c4c4ef5f7bdb9009f6 |
| publicationDate |
2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020323439-A1 |
| titleOfInvention |
Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography |
| abstract |
A method, an apparatus, and a kit including the apparatus and a fluorescence agent are provided for measuring a time-varying change in an amount of blood in a tissue volume, and include exciting a fluorescence agent in the blood, acquiring a time-varying light intensity signal during a pulsatile flow of the blood through the tissue volume, the pulsatile flow having a systolic and a diastolic phase resembling a conventional photoplethysmogram, and processing the acquired signal by applying a modified Beer-Lambert law to obtain a measurement of the time-varying change in the amount of blood in the tissue volume. The instantaneous molar concentration of the fluorescence agent is determined by utilizing a concentration-mediated change in a fluorescence emission spectrum of the fluorescence agent. There is further provided a fluorescence agent for use in the method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11284801-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11564583-B2 |
| priorityDate |
2014-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |