http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020300874-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ef69ad4b35d15d83a37cea41a1ed08a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-4077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-579 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-4005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-281 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 |
filingDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e77a7ba2e62026162d0a9cc5abf501c3 |
publicationDate | 2020-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2020300874-A1 |
titleOfInvention | Method and kit for sample preparation and endotoxin determination |
abstract | The invention relates to a method for preparation of a sample (10) of a formulation (11) for subsequent endotoxin determination, the formulation (11) suspected of comprising an endotoxin, the formulation (11) preferentially being a pharmaceutical formulation. The method comprises the following steps: application of the sample (10) to an endotoxin-free centrifugation column (2) containing a size exclusion chromatography matrix (5) that has been equilibrated with a suitable equilibration buffer (6) and elution of a flow through (15) of the sample by centrifugation, which flow through (15) can then be used for endotoxin determination. The equilibration buffer (6) is selected according to a subsequently used method of endotoxin determination, the equilibration buffer (6) only containing components not interfering with subsequently used method of endotoxin determination. Furthermore, the invention relates to a kit (20) for preparation of a sample (10). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112462015-A |
priorityDate | 2017-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.