http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020291387-A1

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filingDate 2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31d4868a4b11ada385fce9e08dc91552
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publicationDate 2020-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020291387-A1
titleOfInvention Pathogen lysis and nucleic acid extraction method using zinc oxide nanostar
abstract The present invention relates to a method for lysing pathogen lysis and a method for extracting nucleic acid using zinc oxide nanostar, and the method for extracting nucleic acid using zinc oxide nanostar according to the present invention can extract nucleic acids by lysing cells of a pathogen without using a lysis buffer and can extract nucleic acid of high-purity and high-concentration by preventing nucleic acid degradation and fragmentation through various substances including salts contained in the lysis buffer at high concentration. In addition, the zinc oxide nanostar of the present invention (200 to 900 nm) has superior cell lysis capacity compared to the conventional zinc oxide nanoparticles (20 to 50 nm), thereby increasing the nucleic acid extraction efficiency and can extract at room temperature without a heating step to use as a field diagnostic method.
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