http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020289439-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fee0817238d9d83961482f55d2e80ce1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B65B29-028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B65B29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 |
| filingDate | 2020-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_052bf8618258056094841c24749865e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77b96fff24837f9db88d5ed1fc8a99c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcbd1b86d5b8164217c51597b77a7433 |
| publicationDate | 2020-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2020289439-A1 |
| titleOfInvention | Process of Manufacturing a Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation |
| abstract | A process for minimizing formation of a highest degradation product during moist heat sterilization of a drug solution of an oxidation susceptible active pharmaceutical ingredient is provided. The oxidation susceptible active pharmaceutical ingredient is mixed with excipients and deoxygenated water to prepare a non-sterile drug solution. The non-sterile drug solution is filled into a moist heat sterilizable flexible infusion bag. The flexible infusion bag with the non-sterile drug solution is terminally moist heat sterilized at a preset air overpressure between about 0.2 bar to about 1.2 bar to obtain a parenteral drug product. The highest degradation product in the parenteral drug product is less than 0.5% by weight of a labeled amount of the oxidation susceptible active pharmaceutical ingredient in the parenteral drug product. |
| priorityDate | 2013-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.