Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-40 |
filingDate |
2018-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22fcd3bd327dd0292e7402fb7a7eb661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8e986d5450cdd3200648f1e601fde5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c4e5fa8234523d99df6ddd426c316b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19c6f676e5ed8d769ea4907b3eda1e67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e83f0940124ae59fdf919addb6fa9a |
publicationDate |
2020-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020247818-A1 |
titleOfInvention |
Stereoselective process for preparing substituted polycyclic pyridone derivatives |
abstract |
The present invention provides industrially suitable processes for preparing intermediates in the production of substituted polycyclic pyridone derivatives having a cap-dependent endonuclease inhibitory activity. n In the process as shown below, wherein each symbol is as defined in the specification, an optically active substituted tricyclic pyridone derivative of the formula (VII) is obtained in high yield and high enantioselectivity by subjecting a compound of the formula (III) or (VI) to intramolecular cyclization with controlling stereochemistry to obtain a compound of the formula (IV) having a removable functional group on an asymmetric carbon, and then removing the functional group thereof. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261198-B2 |
priorityDate |
2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |