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filingDate 2019-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a1e3fdacc5b2963555f62da979937e9
publicationDate 2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020179296-A1
titleOfInvention Accelerated Clearance of Biologic Therapeutics Using Click-Antidotes
abstract Click chemistry groups attached to both nanoparticles and antibodies to reduce antibody concentration in the body. The nanoparticles with attached click chemistry groups react with the antibody/biologic attached with a corresponding click chemistry group to sequester it in the liver and spleen, effectively and rapidly decreasing the concentration of free antibody/biologic.
priorityDate 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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