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filingDate 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d71348f273682a3ab8feb41f5a05a4a
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publicationDate 2020-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020165380-A1
titleOfInvention Advanced Processing of Absorbable Poly(p-dioxanone) Containing High Level of p-Dioxanone Monomer
abstract The present invention is directed methods of making absorbable poly(p-dioxanone) pellets by melt polymerization of p-dioxanone conducted in a single reactor with a temperature regulator by charging a melt reactor with a mixture of p-dioxanone (PDO) monomer, initiator, catalyst, and optionally a dye; melt polymerizing the mixture in the melt reactor with sufficient agitation of the mixture to allow complete mixing of the monomer and for sufficient time to form a PDO polymer product having an unreacted PDO monomer content of at least 65 mole percent; placing the PDO polymer product under a vacuum to remove at least portion of unreacted PDO; discharging the PDO polymer product from the melt reactor directly into an in-line, underwater pelletizer to produce undried PDO pellets, collecting the undried PDO pellets, and storing the collected PDO pellets in the freezer or a vacuum chamber prior to drying.
priorityDate 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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