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filingDate 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020160936-A1
titleOfInvention Methods for high-resolution microbiome analysis
abstract Methods are presented for binning metagenomic sequences that leverage long reads from a single-molecule long-read sequencing technology and utilize DNA methylation signatures inferred from these reads to resolve individual reads and assembled contigs into species- and strain-level clusters. Methods for deconvoluting prokaryotic organisms in a microbiome sample are presented. Methods for mapping mobile genetic elements to their host organisms in a microbiome sample are also presented.
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