Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6dc876ad016bb47f2d78053a52a9c61d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2035-00465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-3155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2035-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2035-1032 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-0099 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-109 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-1097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-631 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-3151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C18-14 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C18-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-31 |
filingDate |
2018-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a731a0c8b019370abe7b699ea725f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b54d671d32d57fa2287e0a8ffe258ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fece89a6e82032644124a49625b1de71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_549931a791a3652cd7c295b7c739ac8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb8f864bcff15557f0d6b2bed042583d |
publicationDate |
2020-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020158636-A1 |
titleOfInvention |
Flash photo-oxidation device and higher order structural analysis |
abstract |
Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry. The present invention provides new means and methods for the determination of biopharmaceutical HOS and associated conformation using improved devices and methodologies for flash photo-oxidation of proteins to determine their higher order biomolecular structure, and such is responsive to the increased demand for new and improved HOS analytical means in the biopharmaceutical industry. |
priorityDate |
2017-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |