| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b68380e5f86fc7d1b397bb9ea3f8ca51 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N20-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06N20-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-00 |
| filingDate |
2019-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f04b84b1835b99d7ba827a72302df30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e16fba56c07cddacf31886ecfd010a4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dafde4d6f3e396f6dc6bc47e0f989b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b15f53bdfea520d729d1475b93a12419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9c6a70f8e3c2f707fcd64b60b4aa281 |
| publicationDate |
2020-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020118647-A1 |
| titleOfInvention |
Phenotype trait prediction with threshold polygenic risk score |
| abstract |
A system and method predicts a phenotypic trait for an individual. The system identifies a subset of SNP loci with predictive ability of the phenotypic trait. The system calculates a PRS for the individual based on the individual's genetic dataset at the identified subset of SNP loci. The system compares the PRS to a threshold PRS. The threshold PRS is determined by calculating, for each training individual of a plurality of training individuals including some reported to have and some reported to not have the phenotypic trait, a PRS, sweeping through a domain of PRS while calculating a true positive rate and a false positive rate, and then identifying an optimal threshold PRS as the threshold PRS. The system generates a prediction whether the individual has the phenotypic trait based on the comparison. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11765321-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023129750-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3941338-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022087478-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021243094-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021375392-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11308335-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022147700-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022055747-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10936626-B1 |
| priorityDate |
2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |