| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_733f9f206a30eb241a0e7ece400747f1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5421
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2019-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1e64906405b91aa629f4e86272f6e8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01fedeef680406e9a62a223939571f2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51f266f7826ad9b5a3c6f0c0b3a402c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0067b1756b00a69b2833d92c756794a |
| publicationDate |
2020-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020103409-A1 |
| titleOfInvention |
Inhibitors of proteins specific for the secretome of a chondrocyte for use in the treatment of breast cancer metastasis |
| abstract |
The present invention relates to a method for identifying inhibitors of breast cancer metastasis based on a screening with proteins that are specific for the secretome of a chondrocyte, preferably cytokines and/or chemokines. The ligands as identified lead to a decrease of the migration and/or a re-differentiation of a breast cancer cell and/or a reduction of the number and/or size of breast cancer metastases. The present invention further relates to a method for detecting breast cancer metastasis, comprising the step of detecting at least one protein that is specific for the secretome of a chondrocyte, and for methods for treating and/or preventing breast cancer metastasis in a patient in need thereof, comprising the step of administering an effective amount of at least one ligand for one protein that is specific for the secretome of a chondrocyte to said patient in need thereof. |
| priorityDate |
2013-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |