| abstract |
Compounds and embodiments of a method for treating and/or preventing autoimmune diseases are disclosed. The method includes administering to a subject having an autoimmune disease, such as an inflammatory bowel disease, a therapeutically effective amount of a compound according to formula I n n n n n n n n n n wherein X and Y independently are O or NR 1 ; each R 1 is independently H or C 1 -C 6 alkyl; ring A is aryl; each R 2 independently is H, alkyl, alkoxy, amide, cyano, halo, haloalkyl, hydroxyalkyl, heteroalkyl, heterocyclyl, sulfonyl, sulfonamide, or two R 2 groups, taken together with the atom or atoms to which they are attached, combine to form a 4-10 membered ring system; p is 0, 1, 2, 3, or 4; R 3 and R 4 independently are H or C 1 -C 6 alkyl; and R 5 is halo, cyano, or C 1 -C 6 alkyl. |