| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c3c03868c3cbb1941929d9d8bc3f664
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_845dee65a3b9073bfd5dd429d700d189 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-66 |
| filingDate |
2018-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45da63d4b0e52e80d7ce27503151aab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ea52148c143f826105d947f48c31d1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_add0311db15876d78b4d97796facab10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b132e0c1e06f2995d1bf29bf084453ac |
| publicationDate |
2020-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020087263-A1 |
| titleOfInvention |
5-carboxamide-2-thiobarbituric acids and use thereof as medicaments |
| abstract |
The invention relates to a class of 5-carboxamide-2-thiobarbituric acid derivatives which inhibits human type II topoisomerase (topoII) enzyme and to use thereof as medicaments especially for blocking the proliferation of cancer cells and treating cancer. The invention also provides a method for the manufacture of the 5-carboxamide-2-thiobarbituric acid derivatives. |
| priorityDate |
2017-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |