Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46435b49a3b809cefdf9fcd824c98dda |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2313-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2313-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2325-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D63-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D63-082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-262 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D69-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D69-148 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D69-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D63-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D63-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D69-14 |
filingDate |
2019-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba34f6aaf36495c20d41067d58e490b |
publicationDate |
2020-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020086232-A1 |
titleOfInvention |
Affinity chromatography devices |
abstract |
The present invention is directed to affinity chromatography devices that separate a targeted protein or antibody from an aqueous mixture containing the targeted protein or antibody. The chromatography device may contain a stacked membrane assembly or a wound membrane assembly. The membrane assemblies include at least one polymer membrane that contains therein inorganic particles. The polymer membrane and/or the inorganic particles have an affinity ligand bonded thereto. The affinity ligand may be a protein, an antibody, or a polysaccharide that reversibly binds to the targeted protein or antibody. The chromatography device may be repeatedly used and may be cleaned with a caustic solution between uses. The chromatography devices may have a dynamic binding capacity (DBC) of at least 30 mg/ml (or 0.07 micromol/ml) at 10% breakthrough at a residence time of 20 seconds or less. |
priorityDate |
2015-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |