Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62586b0bc63b01be3064a9ecb13e49cc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0011 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-12 |
filingDate |
2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5d03cbe48434beccf4588319d441b57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92f1b0e20362bfcd3980b5ba832a3e2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7c089becfdf06d93135ac6021bf2e6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ffcc85e78e08e4e1295d6736565a207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66a966716378484143f033addd22ab23 |
publicationDate |
2020-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020086012-A1 |
titleOfInvention |
Compound heparin anticoagulant coating liquid, a microsphere for coating and its preparation methods and applications |
abstract |
The present invention discloses a compound heparin anticoagulant coating liquid, a microsphere for coating and its preparation methods and applications. In the present invention, the combination of curcumin and heparin can enhance the anticoagulation functions of heparin coating, and further enhance the stability using the properties of PLA-PEG-PLA drug-loaded sustained-release microspheres, achieving the functions of anti-tissue proliferation and anti-inflammatory reactions that cannot be achieved by coatings alone such as heparin or protein, which is very important for implanted devices such as artificial blood vessels, vascular stents and vascular patches to reduce thrombosis in the human body, lower postoperative complications and improve product lifespan. |
priorityDate |
2017-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |