| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1c62eb67b4b8869198e3a346b1a25c5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-31001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-18 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-49 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6804 |
| filingDate |
2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a5086503bbed7f1847ef95b97eeedc6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_813a91544ce3552d7d5865a07702cb25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_152319c979a1032f8ef3e4125eae0436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3599c13cbb3424f327c691f8dbe8a082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701dec5f6e26bddd1cfbc236f5de00f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e34da32453aefaefb82cfadb64a241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dfa33e83da3614bc8535f53cc9edc01 |
| publicationDate |
2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020071745-A1 |
| titleOfInvention |
Quantification of nucleosome modifications using chemically-defined recombinant nucleosomes |
| abstract |
The invention relates to the use of recombinant/semi-synthetic nucleosomes carrying histone and/or DNA modifications as a reference standard for quantification of covalently modified (on the histone proteins or wrapping DNA), variant, or mutant nucleosomes (collectively “modified nucleosomes” or “nucleosome modifications”) from a biological sample. The invention further relates to methods of using the assay to accurately quantify single or combinatorial nucleosome modifications as biomarkers of disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022094449-A1 |
| priorityDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |