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filingDate 2017-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33e41274eaaddf742f9e0378dc11d352
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca9be17f7accd4be406853d5c99fe54c
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publicationDate 2020-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020062843-A1
titleOfInvention Anti-cd19 humanized antibody and immune effector cell targeting cd19
abstract Disclosed are an anti-CD19 humanized antibody prepared from a murine monoclonal antibody, a chimeric antigen receptor containing the humanized antibody, and an immune cell expressing the humanized antibody. Not only does the humanized antibody of the present invention not produce an anti-antibody response (AAR) and a human anti-mouse antibody response (HAMA), but same also has better affinity than a murine antibody, and has excellent activity and safety, thereby providing a new means for treating CD19-expressing tumors.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359012-B1
priorityDate 2016-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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