Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aff6633139e8f79659a0587cc38a6c07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b74695f4c6259a8598b722c1ef6eefa |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 |
filingDate |
2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00b198472db580d57d4f64200668e293 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9246ca0fdd60e4a620e75f9892e75ef0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f3ae06591fad9910a2b0d382ab7c3d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_792cff51112e6f6dba0da50b9446b907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c916ab5b4551ad3762274dcde3bb4fe1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8a62d3cdbfe01bac02c06c8cc90d8e8 |
publicationDate |
2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020054647-A1 |
titleOfInvention |
Ruthenium complexes for treating cancer which comprises cancer stem cells |
abstract |
The present invention relates to the use of ruthenium(II) complexes for preparing a medicinal product for treating cancer, particularly cancer comprising cancer stem cells. Said ruthenium complexes are capable of selectively metallating guanine quadruplexes, thus resulting in increased expression of the c-MYC oncogene. This increase in the proportion of c-MYC may promote the differentiation of cancer stem cells. |
priorityDate |
2016-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |