| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67d58b186899a1418e18c94878904052 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2019-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_396f00c5670734b7ecf8d6c517f27ae5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d92b0cbc39a311096ddb7305a86594dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0987eb7c9d4f450c9dc359059a0042a |
| publicationDate |
2020-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020046692-A1 |
| titleOfInvention |
Specific akt3 inhibitor and uses thereof |
| abstract |
Methods of selectively inhibiting Akt3 are provided. It has been discovered that 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide selectively inhibits Akt3. Because Akt3 modulates the suppressive function of natural Tregs and the polarization of induced Tregs, 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide can be used for modulating immune responses. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10980878-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291719-B2 |
| priorityDate |
2016-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |