| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab2af750eba92cf72be932a8f6587c29 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14539 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-1451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3277
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-1477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-302
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14546 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
| filingDate |
2017-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_912177b6afdff523b0d1fc7c55654cf9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d83d6fa931b044a58e7104d1daf7425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc5b18bed318ce7ccd3f1014d1e518ec |
| publicationDate |
2020-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020041437-A1 |
| titleOfInvention |
BIOSENSORS WITH pH-INDEPENDENT REDOX MOIETIES |
| abstract |
An electrochemical sensor is provided for use in a wearable device for measuring analytes in a pH-variable biofluid. The sensor includes a plurality of aptamer sensing elements which have biorecognition elements, such as aptamers, that experience a conformational change on interaction with a target analyte in the biofluid. Each aptamer sensing element forms a first configuration before target analyte capture and a second configuration after target analyte capture. A redox moiety is paired with each aptamer sensing element. The redox moiety has a reaction potential that is at least partially independent of a pH value of the biofluid. The EAB sensor further includes an electrode operative in conjunction with the plurality of aptamer sensing elements to produce a variable signal depending upon the configuration of the aptamer sensing elements. |
| priorityDate |
2016-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |