| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0444efde206a2f829562761e58b7e1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c6330535de46698125cb99537999581c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate |
2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e855c58a65e3ac2ac6e13facad858ab4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7148ee3845ebccf79006080cb825e298
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11b2e7f9f28bc601b824518fa1d28696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc88dbf9b9bfd064693838a75279aba1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b802dba85a04665dc966458542c784de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_002afa43ecea46bc7c67a5616609009b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4ff9db62389fed8913e5a5c629492ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac7507835a26018dc74f4fc3df7f976b |
| publicationDate |
2020-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020038332-A1 |
| titleOfInvention |
Method for producing disintegrating particulate composition comprising acid-type carboxymethylcellulose, disintegrating particulate composition comprising acid-type carboxymethylcellulose, and orally disintegrating tablet including disintegrating particulate composition comprising acid-type carboxymethylcellulose |
| abstract |
The present application provides an orally-disintegrating tablet having excellent tablet hardness and disintegrability. The present application further provides a method of producing a disintegrative particulate composition including three components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component and an excipient. The method includes a first wet granulation step using any two of the three components, and a second wet granulation step using granules obtained in the first wet granulation step and the remaining one component of the three components not used in the first wet granulation step. The production method may further includes a crystalline cellulose as a fourth component or a third step of mixing a crystalline cellulose into granules obtained in the second wet granulation step. Disintegrative particulate compositions obtained by these methods are also disclosed. |
| priorityDate |
2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |