| abstract |
A method for producing a genome edited cell or a non-human organism, comprising the step of introducingn (a) an artificial nuclease system which cleaves both ends of a genome editing target region, and (b) a nucleic acid sequence formed by arranging a 5′-side homology arm sequence, a donor DNA sequence, and a 3′-side homology arm sequence in this order from a 5′-side, the 5′-side homology arm sequence being a homologous sequence of one nucleic acid sequence outside the genome editing target region, and the 3′-side homology arm sequence being a homologous sequence of the other nucleic acid sequence outside the genome editing target region,n into a cell or a non-human organism. |