http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020024298-A1

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filingDate 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020024298-A1
titleOfInvention Process for the preparation of fluticasone propionate form i
abstract The invention relates to a novel crystallisation process for preparing fluticasone propionate as crystalline form 1 polymorph with controlled particle size and suitable for micronisation. Said process comprises the step of dissolving fluticasone propionate in acetone or in a mixture of acetone and water and then adding this solution to water or to a mixture of water 10 and acetone, thereby causing fluticasone propionate to crystallise out of the solution as crystalline form.
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Total number of triples: 24.