http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020017537-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5d8e773f6014d38db0057617c487651 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-16 |
| filingDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_513d1a953d56723d78de1768a92fcc5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d4489537d02cae29f3efb23c2a81843 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31120511dbec3b3da41a527f3ff3b55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4a3595132e8897425ec9e812c4c96a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1fe7b167362c6cacde40627066540bf |
| publicationDate | 2020-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2020017537-A1 |
| titleOfInvention | Lincosamide derivatives, preparation and use thereof as antimicrobial agent |
| abstract | Lincosamides of general formula I, where R1 is selected from C2-C8 alkyl or C2-C8 alkenyl; R3 is selected from OH, O(C1-C4 alkyl), SH, S(C1-C4 alkyl) or halogen; R4 is H or C1-C3 alkyl; each of R21, R22, R23, R24, R25 is independently selected from the group consisting of H, OH, C1-C4 alkyl, C1-C4 alkenyl, C1-C4 alkynyl, halogen, O(C1-C4 alkyl), O(C1-C4 alkenyl), O(C1-C4 alkynyl), NH 2 , N(C1-C4 alkyl) 2 , N(C1-C4 alkenyl) 2 , N(C1-C4 alkynyl) 2 ; and pharmaceutically acceptable salts thereof. A method of preparation thereof, in particular a biosynthetic method using newly discovered functions of celesticetin biosynthetic proteins Ccb1 and/or Ccb2. Lincosamides of general formula I are suitable for use as antibacterial and antiprotozoal substances. |
| priorityDate | 2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.