| abstract |
Disclosed herein are novel chimeric antigen receptors (CARs) targeting human LHR, B7-H4, HLA-G, or HLA-DR, and therapeutic methods of their use. LHR, B7-H4, HLA-G, or HLA-DR are expressed in the context of many human cancers including thyroid, prostate, colon, breast, ovarian, and renal cancers, as well as B-cell leukymias and lymphomas. |