http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020003785-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c930c1a3fcc9a93dc304ab4a77bd0ea3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b01dcd61775e996fac631d4b10c4e87f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-54 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a80d69e6550378a5dec0e8cba06ba67e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5e41dc44a6ee166550dfef4dacd74c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f1d3b5bd759f3fe4f6b99b48d4ccced |
| publicationDate | 2020-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2020003785-A1 |
| titleOfInvention | Use of anti-uchl1 igg plasma concentration for diagnosing idiopathic steroid sensitive nephrotic syndrome |
| abstract | The present invention relates to methods and kits for diagnosing Idiopathic steroid sensitive nephrotic syndrome. The inventors showed that idiopathic nephrotic syndrome (INS) patients display a significant plasma level of anti-UCHL1 IgG that target the podocytes. Based on the correlation between the plasma level of anti UCHL1 IgG and proteinuria, they suggested that anti UCHL1 IgG plays a central role in the development of massive proteinuria. In particular, the present invention relates to a method of determining whether a subject suffers from idiopathic steroid sensitive nephrotic syndrome (INS) comprising i) determining the concentration of plasma anti-UCHL1 IgG in a sample obtained from the subject ii) comparing the concentration determined at step i) with a predetermined reference value and iii) concluding that the subject suffer from idiopathic steroid sensitive nephrotic syndrome when the concentration determined at step i) is higher than the predetermined reference value. |
| priorityDate | 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1729.