Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9a66b0bf1cce655ea85ad7221bba215 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-518 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1068 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13e30fcd9fa55fae970ad3ca1128e7a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88111dcf98c170d016b65d66a6619c3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8afbe91f993378f5d227796b8aad9a1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2a2ae73f704e0919d530d114b42284d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c6a64ff5e19bc0bedfb8216ca9b047b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbc2e0ebe9c45e6047977837a33ca648 |
publicationDate |
2020-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020002762-A1 |
titleOfInvention |
Method and system for sequencing nucleic acids |
abstract |
Provided are compositions, methods and systems for determining the sequence of a template nucleic acid using a polymerase-based, sequencing-by-binding procedure. An examination step involves monitoring the interaction between a polymerase and template nucleic acid in the presence of one or more nucleotides. Identity of the next correct nucleotide in the sequence is determined without incorporation of any nucleotide into the structure of the primer by formation of a phosphodiester bond. An optional incorporation step can be used after the examination step to extend the primer by one or more nucleotides, thereby incrementing the template nucleotides that can be examined in a subsequent examination step. The sequencing-by-binding procedure does not require the use of labeled nucleotides or polymerases, but optionally can employ these reagents. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447823-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10655176-B2 |
priorityDate |
2016-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |