Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1faac18f8237eeb75b8f335cefa6139f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fffda8b59ac378c0e7cd94cdf51bbfd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 |
filingDate |
2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93a394276cdfaab1bd3a020e8ea43882 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce2178fa497f1742cfcd226ba4c42d8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a2eb1a877656a3252e8cf9f5b0b8197 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_602f279447e8b5b02ff070a7f02e0d80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_185f10702aafe40aac723c870e138460 |
publicationDate |
2020-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020000971-A1 |
titleOfInvention |
Nerve repair scaffolds having high microchannel volume and methods for making the same |
abstract |
Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129701-B1 |
priorityDate |
2015-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |