http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020000724-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc8f334fd722f43191d4f5020c1d1cf0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 |
| filingDate | 2019-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171026c7e3a95d6920edc5ecf13211ac |
| publicationDate | 2020-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2020000724-A1 |
| titleOfInvention | Process for producing a nano-cbd liposome system |
| abstract | The present invention relates to a process of producing a nano-CBD liposome system comprises: (i) preparing a dispersal phase by dissolving CBD in an ethanol solvent in a ratio between mass of CBD:volumn of ethanol solvent as 8:10 by a stirrer at a speed of 300 to 500 rpm and simultaneously heating to a temperature ranging from 40 to 60° C. within 4 to 8 hours; (ii) preparing a liposome carrier consisting of lecithin, olive oil in a ratio by mass of 1:3 mixed in a themostatic bath at a temperature from 40 to 60° C. to ensure that lecithin completely dissolves in oil, stirring homogeneously; (iii) adding the carrier to the dispersal phase in a ratio by mass of 40:60, continuing heating the dispersal phase to a temperature ranging from 40 to 60° C., stirring at a speed of 800 to 1000 rpm for 1 to 2 hours; (iv) cooling the resulting mixture to 25° C. and injecting one volumn of distilled water between 1 and 1.5 L by using hight-frequency nozzles at a frequency of 60 Hz, drop sizes ranging from 10 to 20 μm, injecting capacity of 10 ml/min, with the temperature of distilled water of 25° C., giving a liposome suspension-water solution; (v) homogenizing the mixture of liposome suspension-water solution by injecting through 30 Mpa high pressure homogenizers to obtain a nano-CBD liposome system which is a homogeneous, stable mixture ensured with the particle sizes <200 nm. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113616603-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113041234-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022259126-A1 |
| priorityDate | 2019-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.