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publicationDate 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2019383556-A1
titleOfInvention Method of microwave vacuum drying spherical-shaped pellets of biological materials
abstract Methods for preparing dried pellets of biological materials are described. The pellets can have a substantially spherical shape and are prepared by freezing droplets of a liquid composition of a desired biological material on a solid surface followed by microwave vacuum drying the frozen droplets. These methods are useful for preparing dried pellets having a high concentration of a desired biological material, in particular a therapeutic protein or vaccine, and which have a faster reconstitution time than lyophilized powder cakes prepared in vials.
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