Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 |
filingDate |
2018-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8236d4f207490ab468b61fae43515f26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_789553760071c98c022332c66a6c9739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a9cccc01e9b31226d14b20873a8c93d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0860a078acaa12e8ed0e6c9a9f126d1 |
publicationDate |
2019-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019359612-A1 |
titleOfInvention |
Process for the Preparation of Crystalline Form C of Avibactam Sodium |
abstract |
The invention relates to a process for the preparation of avibactam sodium in polymorphic form C comprising the steps (i) providing a mixture comprising avibactam or a salt thereof and a solvent, wherein the mixture has a water content of less than 2% by weight based on the weight of the mixture; (ii) increasing the temperature of the mixture provided in (i) to at least 55° C. and providing a positive pressure; adding a sodium source to the mixture in step (i) and/or (ii) if the form of avibactam provided in (i) is not avibactam sodium; thereby obtaining avibactam sodium in polymorphic form C. |
priorityDate |
2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |