| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82b460ae2c0d553a2db7abd984e85631 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2066
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54 |
| filingDate |
2019-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3c47fa57b113732265a02375e77437e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b254880298dca1761527b69d3cd5c99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76d62cffdaa53af2fa02be7dfb0ce698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af69ede49452f424fb5e4082a0fc9c7f |
| publicationDate |
2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019336582-A1 |
| titleOfInvention |
Compositions and Methods for Modulating IL-10 Immunostimulatory and Anti-Inflammatory Properties |
| abstract |
The invention provides compositions and methods for modulating the immunostimulatory properties and/or anti-inflammatory properties of IL-10. The present invention provides scIL-10 polypeptides of Formula 1. The polypeptides of the invention are optionally linked to a fusion partner. The polypeptides of Formula 1 are referred to herein as “scIL-10” polypeptides and comprise an amino acid sequence arrangement from N-terminus to C-terminus in accordance with Formula 1: n (first monomer subunit)-LINKER-(second monomer subunit) Formula 1n n wherein the first monomer subunit, the second monomer subunit or both the first and second monomer subunits may be independently selected from: an unsubstituted IL-10 monomer subunit; or a substituted IL-10 monomer subunit comprising at least one amino acid substitution; and wherein LINKER is any amino acid linker of at least 1-100 amino acids in length. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11214606-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11160869-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11673930-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466067-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479593-B2 |
| priorityDate |
2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |