| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620d8e0b5ce849d2ace9151c7b23d596 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2017-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ed2d2e9305e9d7689b74597beb597d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88d12fab49f615aa7aa2d8289620552f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b066350ca3b7c6f7ceccb507c865ae1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c91606719a87f31b8acd0cb0b1974fd |
| publicationDate |
2019-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019298786-A1 |
| titleOfInvention |
Extracts of saudi arabian herbal plants, anti-cancer method using such extracts, and cytological profiling using automated high-content imaging technique |
| abstract |
Cell-based phenotypic profiling and image based high-content screening are used to gain insight into the mode of action and potential cellular targets of plants historically used to determine anti-cancer activity of Saudi Arabian plants Juniperus phoenicea (Arar), Anastatica hierochuntica (Kaff Maryam), and Citrullus colocynthis (Hanzal). The cytological profiles of fractions taken from the plants were compared with a set of reference compounds with known modes of action. Cluster analyses of the cytological profiles were performed, which revealed detailed information on the modes of action of the tested compounds as potential topoisomerase inhibitors. Cytological profiles showed that some of these compounds inhibited cell proliferation causing cell cycle disruption. |
| priorityDate |
2016-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |