http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019292190-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98cb1b197f761c87cd3caf32bc247e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2017-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b9faf6a5787ec5065b436f983680ef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bdabb8eef64ec9b86305d3d9f582bcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa772eb172dd10d3a5964cc44fed694 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d3f1fd8b899a095dbfff842edf9ef4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27e1f7b14999b26bda3534eb5e42390d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f4fc646b31a2c657bccc63334a5e23b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d00655d0169c60ce16087587d201fc |
| publicationDate | 2019-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2019292190-A1 |
| titleOfInvention | Novel 5h-pyrrolo[2,3-d]pyrimidin-6(7h)-one derivative |
| abstract | The invention of the present application provides a compound represented by Formula (I) or a salt thereof, which exhibits an inhibitory activity against at least one kinase selected from the group consisting of Akt kinase, Rsk kinase, and S6K kinase and/or a cell proliferation inhibiting effect and is useful as a prophylactic and/or therapeutic agent for diseases associated with the above-mentioned kinases, particularly cancer. [In the formula, R 1 represents a 4- to 6-membered monocyclic unsaturated heterocyclic group which has 1 to 3 hetero atoms independently selected from N, S and O and may have a substituent; R 2 represents a hydrogen atom or the like; R 3 , R 4 , and R 5 , may be the same as or different from one another and independently represent a hydrogen atom or the like; R 6 represents a hydrogen atom or the like; R 7 and R 8 , may be the same as or different from each other and independently represent a hydrogen atom or the like; X 1 and X 2 may be the same as or different from each other and independently represent N or CR 9 ; R 9 represents a hydrogen atom or the like; and X 3 represents N or CH when the broken line ( ) represents a single bond, and represents C when a broken line indicates a double bond, wherein at least one of X 1 or X 2 represents N.] |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115850244-A |
| priorityDate | 2016-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 500.