| abstract |
The present invention provides a method of administering a pharmaceutical composition comprising anti-RANKL antibodies, calcium and vitamin D to a patient in need thereof. The method includes either administering a pharmaceutical composition comprising the anti-RANKL antibodies at a dose of 30 to 90 mg in 1-2 ml of a solution at yearly or six-month intervals, orally administering a pharmaceutical composition comprising the calcium at a dose of 400-600 mg daily, and orally administering the vitamin D at a dose of 800-1200 IU of vitamin D daily, or subcutaneously administering the anti-RANKL antibodies at a dose of 60-180 mg in 1-3 ml of solution for at least 3 weeks, orally administering the calcium at a dose of 400-600 mg daily, and orally administering the vitamin D at a dose of 800-1200 IU daily. |