| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a60649a09a47690f2c5082c03fbc2212
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df874e3cf88adba3792dc9d5b5776180 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-741 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-741
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a487595637a23ff53ffd3210110e557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a012bf5d6380cdfac2880e3c0b76b5e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ce21d63bd1a29170ac20ce6552e1de8 |
| publicationDate |
2019-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019282632-A1 |
| titleOfInvention |
Methods and products for modulating microbiota composition for improving the efficacy of a cancer treatment with an immune checkpoint blocker |
| abstract |
The present invention relates to the role of the microbiota in the efficacy of cancer treatments with a drug blocking an. immune checkpoint and provides methods and probiotics to improve the efficacy of such a treatment in patients in need thereof. More particularly, the invention pertains to the use of vancomycin or penicillin to modulate the gut microbiota to potentiate the anticancer effects of anti-CTLA4 molecules. B. fragilis or fecal microbial transplantation of a defined composition enriched in immunogenic Bacteroides spp. can also be used as a probiotic to that aim. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021133812-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11376285-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11439671-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022040592-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023134210-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023134202-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023134206-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023134200-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541105-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023134204-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022125914-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114306615-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021061789-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114469986-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114404598-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115806893-A |
| priorityDate |
2014-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |