http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019265251-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe2d8a10ec14cd3998ef9c0637e811b1 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2018-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b55a8f89b7fcf37055088d12cbcefc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45eaf4082f1cad88003ecb78cc25644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6933ed9747845b97f32d2050ea62b13c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1608081e8f77cd7faacde47b518767a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_050ea35c86d851cb7b5a186b8d2e2317 |
publicationDate | 2019-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2019265251-A1 |
titleOfInvention | Proteomic Biomarkers of Sepsis in Elderly Patients |
abstract | A proteomic expression platform to identify age-related sepsis risk is disclosed using patients with an intra-abdominal infection. A semi-quantitative plasma proteomics workflow was applied which incorporated tandem immuno affinity depletion, iTRAQ labeling, strong cation exchange fractionation, and nanoflow-liquid chromatography coupled to high resolution mass spectrometry. A protein profile was determined that exhibit statistically significant differences in expression levels amongst patients with severe sepsis as a function of age. Representative pathways that are differentially-expressed include, but are not limited to, acute phase response, coagulation signaling, atherosclerosis signaling, lipid metabolism, and production of nitric oxide/reactive oxygen species. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022232698-A3 |
priorityDate | 2013-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1493.