| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e513c7b150cb28b23f395e699402b5b6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01022 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-40 |
| filingDate |
2019-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13398cd9e5d3d912542ecd3d5023d780
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e26f9b5146197a17df1f69ddfbc84ac9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65cc9173d38bd2bb03708939397c29e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda63e182d984eea20ac1eb8597e1f37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1118ac379d4bc47337af7114499cfd7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_375645c532ca6397ec2422fa45fa9a3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1daa331a71b82d680dfe5c87ee2a65a9 |
| publicationDate |
2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019256832-A1 |
| titleOfInvention |
Stabilized alpha-galactosidase and uses thereof |
| abstract |
Multimeric protein structures comprising at least two alpha-galactosidase monomers being covalently linked to one another via a linking moiety are disclosed herein, as well a process for preparing same, and methods of treating Fabry disease via administration of a multimeric protein structure. The disclosed multimeric protein structures exhibit an improved performance, in terms of enhanced activity and/or a longer lasting activity under both lysosomal conditions and in a serum environment. |
| priorityDate |
2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |