http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019241615-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0001a01a79f5f5d068a6b44928ba9cfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_058275b424fec007feb92ef134ba4ece |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
filingDate | 2017-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a9a863d60162261f9c201445390ec84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d69f0f12fed8186883c0488da2052c2 |
publicationDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2019241615-A1 |
titleOfInvention | Cyclic peptide inhibitors of hedgehog proteins |
abstract | Cyclic peptide compounds are provided that can bind to one or more homologs of Hedghehog signaling proteins and block their interaction with the Patched receptor. These compounds are useful for suppressing Hedgehog-dependent stimulation of the Hedgehog pathway in cells and in living organisms. Methods for using the cyclic peptide compounds, and compositions comprising them, for treatment of cancers and other diseases which are characterized by aberrant Hedgehog-dependent activation of the Hedgehog pathway and/or which can benefit from chemical suppression of Hedgehog-dependent signaling are also disclosed. |
priorityDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1227.