| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48047aa02d20829938b62a42950b3b84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R1-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-445 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d380bbe2a587e3f25e694fcec0bbdd74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f965b9252c8691cc72f9296df783152
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e019fd297502321b43c9f70252eba050
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_938eb85cc08c3f6f637ca45f4a6e68c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_492bcc78c0519123cb9f88d29b1c4325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d183b4758184939bd236d77c8240a9ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b65e4c4facb50c234d36bc17814df1 |
| publicationDate |
2019-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019233906-A1 |
| titleOfInvention |
Mutant strains of staphylococcus aureus with multiple inactivated tcs systems |
| abstract |
Novel strains of Staphylococcus aureus and uses thereof. The invention provides mutant strains of S. aureus devoid of all non-essential two-component signal systems (TCSs) and even the essential walKR system, the intermediate mutants devoid of a number of TCSs and their uses as research and biotechnological platform. The mutants devoid of all non-essential TCSs are viable, stable under laboratory growing conditions, genetically manageable and capable to express heterologous proteins. Having them allows individual analysis and targeting of each TCS, its individual complementation and obtaining information about the sensing systems that can be useful for biotechnological applications based or directed to S. aureus, such as the identification of novel antimicrobials. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114480387-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113088477-A |
| priorityDate |
2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |