Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6784372aa482f6c62b3c468693641159 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21021 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6437 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
filingDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8140641f298645426b75295f028a9f02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aea80771a87a87c4c6674da209222a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c07a5532f65f630f372e588d22ec113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44edb7b257d4276c3d42634c2d994a66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c0643dec6e460ac808111aff3e342d6 |
publicationDate |
2019-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019225957-A1 |
titleOfInvention |
Chimeric clotting factors |
abstract |
The invention provides chimeric clotting factors comprising an activatable clotting factor and an enhancer moiety. The activatable clotting factor allows the chimeric clotting factor to be activated at the site of coagulation. The enhancer moiety can additionally improve procoagulation activities of the chimeric clotting factors. The chimeric clotting factors can further be improved by fusion to a half-life extender, which improves a pharmacokinetics property of the chimeric clotting factor. The invention also includes methods of making and methods of using these chimeric clotting factors. |
priorityDate |
2012-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |