Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae10212794160b34478f0d05b6ab6fd7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91074 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-104 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2019-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_686cc94c04f0591d42248a8748f40529 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aad99fd8db7a435e0ba44875cf5e82db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a832832343c778392c29043f55b3b975 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47ed7f12691622ad7f9b5c7ddd1a14fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f492e7af5bd9e44d41a8c12053064ba0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc89b72593fd856cc81c1f1e077be17a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60c42ed61d8224bf6fde6dcca40852f4 |
publicationDate |
2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019219562-A1 |
titleOfInvention |
Methods for screening cereblon modifying compounds |
abstract |
A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL4; administering the cereblon modifying compound to the sample; determining a second protein level of SALL4; comparing the first level and the second protein level of SALL4 to determine if the cereblon modifying compound induces degradation of SALL4; and selecting the cereblon modifying compound that does not induce degradation of SALL4. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023009719-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023122726-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022153220-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787800-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11767330-B2 |
priorityDate |
2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |