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filingDate 2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2019211326-A1
titleOfInvention Hc-cdr3-only libraries with reduced combinatorial redundancy and optimized loop length distribution
abstract The present invention provides for a library of vectors comprising human HC-CDR3 regions of varying length, wherein the diversity of said library is focused on the HC-CDR3 region only and diversity has been optimized such that redundancy is reduced for short HC-CDR3 loops and coverage of HC-CDR3 region variants for longer loop lengths has been increased. The library of the present invention is displayed on phage for selection against target antigens.
priorityDate 2016-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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