| abstract |
A composition and a method for improving sensitivity and specificity of detection of nucleic acids, use dCas9 and gRNA, which binds to a target nucleic acid sequence, in amplification of nucleic acids including DNAs, RNAs, and the like increases efficiency in amplification of nucleic acids and thereby can ultimately improve sensitivity and specificity of a target diagnosis on the basis of a functional difference between Cas9 and dCas9. |