http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019172557-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfcf60057abf4c36ff2c088bc7ea587c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-00 |
filingDate | 2018-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30b0319e6f8906a6e7667c6f7c2585ea |
publicationDate | 2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2019172557-A1 |
titleOfInvention | Rule-Based System to Detect Metastatic Cancer Stemming from a Colorectal Tumor and to Determine a Proposed Treatment Regime |
abstract | Rule-based apparatus and kit to detect metastatic cancer in a patient having a colorectal tumor. Apparatus has inputs to receive patient data comprising expression levels of genes from hepatic tissue, a memory that stores reference values of corresponding genes of persons free of colorectal tumors, a processor that interprets significance of overexpression and/or underexpression of selected patient data genes relative to reference values, and an output responsive to the processor to produce an indication confirming or annulling hepatic metastasis. Specific genes in questions include group 1 genes (PRDX4, CRP, ID1, MT1E, TNFSF14, MRC1, ICAM1, IL18, IL10, TFN) and group 2 genes (NGF, EPHA1, ERBB2IP, SDC1, COL18A1, KNG1, ADH1 B, CYP2E1). Analysis may be performed on protein signatures of genes rather than genes themselves. A kit to assist a user to produce patient data comprises a low density genetic expression array or protein array for measuring genetic expressions or protein signature, as well as instructions for using the kit. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112220925-A |
priorityDate | 2017-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.