| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-128
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-507
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-28 |
| filingDate |
2017-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e03d095ee275fc951e14e73844be015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8f80e82382e483d6501a7ecc3f0bd75 |
| publicationDate |
2019-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019125929-A1 |
| titleOfInvention |
Compositions and methods for grafts modified with a non-thrombogenic and pro-migratory cell-derived extracellular matrix |
| abstract |
The present invention relates to novel compositions and methods for reducing or eliminating the thrombogenicity of a graft by modifying the graft with a cell-derived extracellular matrix lacking thrombospondin-2 (TSP2-null ECM) to render it non-thrombogenic when transplanted to a subject in need thereof. The invention also provides a method for improving the biocompatibility of a medical device or an implant by modifying the medical device or implant with a cell-derived TSP2-null ECM, whereby the medical device or implant is rendered non-thrombogenic and pro-migratory. |
| priorityDate |
2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |