| abstract |
Compositions comprising a biguanide derivative like chlorhexidine are disclosed for use in methods of preventing bacterial growth in a wound or surgical site of a subject. The methods involve irrigating or coating the wound or surgical site with the solution and then closing or covering the wound or surgical site without washing the solution from the wound or surgical site with saline or water. Articles such a breast implants, tissue expander, titanium implants, tubes, surgical drains, and devices designed to ease the insertion or for sterile insertion of implants (e.g. funnels) that are coated with a biguanide derivative are also disclosed. |