| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62ce28ca279c019c9e54c616e627879f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F2217-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2210-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-20081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F2111-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F17-5018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F30-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-707 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06T7-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06T17-00 |
| filingDate |
2018-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f24ff18ffa3d2831a9bf3fd79745378f |
| publicationDate |
2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019108322-A1 |
| titleOfInvention |
System And Method For Computing Drug Controlled Release Performance Using Images |
| abstract |
A method for computing the release rate of a controlled release drug and medical device using a combination of imaging data and computational physics is described. The method employs a three-dimensional digital representation of a drug sample, derived from two-dimensional or three-dimensional imaging, which captures the drug active pharmaceutical ingredient (API), excipients, and porosity with distinctive contrasts. Direct numerical simulations are conducted on the three-dimensional digital representation to derive effective transport properties of the API going through a porous matrix or membrane. Drug release rate can be predicted more efficiently than laboratory-based methods. When there is strong heterogeneity presented in the drug, a further method is described that engages imaging and release simulations at multiple scales. Computerized systems and programs for performing the methods are also described. |
| priorityDate |
2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |