| abstract |
The invention relates to a method for initiating the replication of a deoxyribonucleic acid molecule, said method comprising a step of inserting, into said deoxyribonucleic acid molecule, at least one nucleic acid molecule representing a multicellular DNA replication origin, the replication origin comprising at least nine nucleotides, the at least nine nucleotides consisting of at least three uninterrupted origin repeating elements (OGRE). |