Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_047947772c630c060c95cb7d40545dab |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2017-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f05506f715f7b1209052d934d0326cc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d365f6e5ff890ea8ba4414b8ac9802b |
publicationDate |
2019-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019092825-A1 |
titleOfInvention |
Inhibitor of astrocyte tnf alpha for use in the treatment of neurological diseases |
abstract |
Disclosed is a human mutated form of NGF including two mutations, a first mutation being represented by the substitution of the proline amino acid in position 61 with a serine, a second mutation being represented by the substitution of an amino acid in any one of the positions 95-101, for simultaneous use as agent for the activation of the chemokine SDF-1alpha and as agent for the inhibition of the activity of the cytokine TNF alpha. |
priorityDate |
2016-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |